Saturday, December 24, 2011

House GOP agrees to payroll tax patch

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Source: http://www.delawareonline.com/article/20111222/NEWS/111222042/1032/rss0209

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Jason Miller agrees with Dana White about his performance

Jason Miller agrees with Dana White about his performanceAfter Jason "Mayhem" Miller lost to Michael Bisping at "The Ultimate Fighter" season 14 finale earlier this month, he took a verbal beating from UFC president Dana White. He called it the worst stand-up and the most lopsided fight he has ever seen.

A disappointed Miller is now training in Holland, and responded to White's comments on his own website.

Dana White was right. He made some disparaging comments about my performance, and I agree with him. I displayed the worst of everything that night in the octagon. I was tense in round one and I locked up after that. I didn't perform to my potential, and I take full responsibility for it. That wasn't a UFC caliber performance, and I'm not happy about it.

After reading about Antonio Rodrigo Nogueira blame his loss on referee Herb Dean, it's refreshing to hear Miller take such responsibility for his loss. He also said that he is taking this loss as a challenge, and ended it with a little bit of an inspirational speech.

My challenge to you, and myself, is to continue to press on and make the most of your adventure here on earth. At the end of your life you want to be sure that you've made your best effort to make a collection of epic stories. Some sorrowful ones, some happy ones and some downright amazing, but the challenge for you is to find and make the most of each of these adventures.

That was the exact inspiration I needed to go finish my Christmas shopping.

Source: http://sports.yahoo.com/mma/blog/cagewriter/post/Jason-Miller-agrees-with-Dana-White-about-his-pe?urn=mma-wp11006

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Friday, December 23, 2011

Women's Basketball: Mason vs George Washington

Today @ Mason Event Calendar - George Mason University
To include your events on the Today@Mason Calendar, you can Fill Out the Request Form,
or e-mail gmutoday@gmu.edu. Inquiries about a specific event
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Women's Basketball: Mason vs George Washington

  • December 22, 2011 at 7:00 pm

Patriot Center

Patriot Center Box Office, (703) 993-3000

Web Site

Source: http://today.gmu.edu/57938/

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Houston man paying $1 parking ticket 58 years late

(AP) ? A Houston man says he wants to clear his own conscience and pay a $1 parking ticket he got 58 years ago, even though the city's traffic violation records have been purged.

Dale Crawford sent a letter to city officials after finding the ticket among some keepsakes. He says it's a debt that he wants to pay, though it's a "small, almost unnoticeable amount."

Crawford received the ticket Feb. 3, 1953, the day he was inducted into the Army. He left his 1946 Nash at a parking meter at the induction station. When his dad was late retrieving the car, it had been ticketed.

Houston Mayor Annise Parker says she'll personally accept Crawford's payment Wednesday and thank him for setting an example for others who owe debts to the city.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/aa9398e6757a46fa93ed5dea7bd3729e/Article_2011-12-20-US-Old-Ticket/id-5261d0c6b3c24fcd9664689a38a7199f

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Monday, December 19, 2011

Gene discovered for Weaver syndrome

Friday, December 16, 2011

Scientists have found a gene that causes Weaver syndrome, a rare genetic disorder that typically causes large size at birth, tall stature, developmental delay during childhood, and intellectual disability. Published today in the American Journal of Human Genetics, the discovery means that testing the EZH2 gene for mutations could help families who are seeking a diagnosis for their child.

"For the families among whom we identified the gene, this discovery definitively brings the diagnostic odyssey to a close ? it's DNA confirmation that their children have Weaver syndrome," says Dr. William Gibson, the study's lead investigator. Dr. Gibson is a clinician scientist at the Child & Family Research Institute at BC Children's Hospital and an assistant professor in the Department of Medical Genetics at the University of British Columbia (UBC).

"Our discovery enables DNA-based diagnostic testing for this particular disease," says Dr. Gibson. "For physicians who suspect Weaver syndrome in one of their patients, we can now confirm it if we find mutations in EZH2. There may still be other Weaver syndrome genes, and we need to study more families to be sure."

Presently, doctors diagnose Weaver syndrome by assessing a child's face, growth, skeleton and other clinical features. People with Weaver syndrome have an oversized head, typical facial features, problems with muscle tone and joints, and differences in the way their skeleton matures. Mutations in the NSD1 gene, which normally causes a rare disease called Sotos syndrome, are also known to cause Weaver syndrome in some cases. There may be other genes involved in Weaver syndrome that are yet to be discovered.

"Now we have an answer for these families and we are also in a position to provide answers to other families affected by this rare and difficult disease," says Dr. Gibson. He is available to see new patients clinically for diagnosis of Weaver syndrome. As a result of this discovery, Dr. Gibson's team now offers sequencing of the EZH2 gene on a research basis in partnership with the Ottawa Hospital Research Institute. Dr. Gibson's team can be contacted by email at wtgibson@cfri.ubc.ca.

Traditionally, hunting for a disease-causing gene has relied on tracking a gene throughout a family's history. However, Weaver syndrome usually occurs only once in a family, as it is thought to be caused by a new genetic mutation in the sperm or egg that conceived the child. For this study, the investigators sought patients with Weaver syndrome from Canada and the United States. They approached Dr. David Weaver, who discovered the syndrome in 1974 and is professor emeritus of Medical and Molecular Genetics at Indiana University School of Medicine in Indianapolis. In two families that Dr. Weaver had examined, the Canadian team looked for brand new genetic mutations by comparing the DNA of affected children to DNA from their unaffected parents. Once the investigators identified EZH2 as a candidate gene, they sequenced it in DNA samples from a third Canadian family. They confirmed that an EZH2 mutation was in this third family's child but not in either of her healthy parents.

EZH2 is a cancer gene that is known to be mutated in leukemia, B-cell lymphomas and some other blood cancers. The gene helps control how DNA is packaged around specific proteins, which in turn helps to regulate which groups of genes are turned off and on.

"Our finding illuminates an emerging area of biology that links developmental syndromes and cancer," says Dr. Gibson. "It appears that some mutations in EZH2, if these occur early in life, produce developmental syndromes such as Weaver syndrome, whereas mutations in the same gene that occur later in life can produce cancer."

Dr. Steven Jones is the study's senior author who led the DNA sequencing and bioinformatics. He is head of bioinformatics and associate director of the Michael Smith Genome Sciences Centre at BC Cancer Agency, professor in the UBC Department of Medical Genetics, and professor, Molecular Biology & Biochemistry at Simon Fraser University (SFU).

###

Child & Family Research Institute: http://www.cfri.ca/

Thanks to Child & Family Research Institute for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/116102/Gene_discovered_for_Weaver_syndrome

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Sunday, December 18, 2011

Syrians protest against Assad after Russia U.N. move (Reuters)

BEIRUT (Reuters) ? Hundreds of thousands of Syrians took to the streets on Friday to protest against President Bashar al-Assad, activists said, a day after Syria's big power ally Russia sharpened its criticism of Damascus in a draft United Nations resolution.

Activists and residents said Syrian forces shot dead four people in a continuing crackdown that the United Nations says has killed 5,000 people in the last nine months and has provoked Western and Arab League sanctions to isolate Damascus.

Friday's killings took place, activists said, after midday prayers in the eastern city of Deir al-Zour and in Homs, hotbed of opposition to four decades of repressive Assad family rule.

In Homs 200,000 people joined a protest march, the British-based Syrian Observatory for Human Rights said, and footage broadcast by Al Jazeera television showed mock gallows where five effigies were hanged, including one of Assad.

It was not possible to verify the number of protesters as Syria has barred most independent journalists, but if true it would be one the biggest turnouts for several weeks.

Russia on Thursday presented a new, beefed-up draft resolution on the violence to the U.N. Security Council, offering a chance for the 15-nation panel to overcome deadlock and deliver its first statement of purpose on Assad's crackdown.

The council has been split between Western countries harshly critical of Syria on the one hand, and Russia, China and non-aligned countries on the other that have refused to pin the main blame on Assad for the violence.

Western diplomats believe a firm Security Council resolution backed by Russia, Syria's longstanding ally and arms supplier, could make a real difference to efforts to tackle the crisis.

Assad has denied that Syrian forces have been given orders to kill demonstrators, blaming armed groups for the violence. He said 1,100 soldiers and police have been killed since the uprising erupted in March, inspired by other unrest in the Arab world that has toppled three autocratic leaders this year.

An armed insurgency has begun to eclipse civilian protests, raising fears Syria could descend into civil war. On Thursday army deserters killed 27 soldiers and security personnel in the southern province of Deraa, the Observatory said.

It is the most serious challenge to the 11-year rule of Assad, 46, whose family is from the minority Alawite sect that has dominated majority Sunni Muslim Syria since 1970.

The United States and European Union have imposed sanctions and called on Assad to step down. Neighboring Turkey has taken similar steps and even the Arab League has declared sanctions against Syria, although it has several times extended a deadline for Syria to approve a formula for ending the crisis.

In the latest sign of the heavy economic price Syria is paying for the bloodshed, Turkey said on Friday that Damascus would lose more than $100 million a year in transport revenues as Ankara bypasses the turbulent country by opening alternative export routes to the Middle East and Gulf.

The Turkish Economy Ministry said it had finalized talks to start exporting goods to Egypt via sea in January and from there overland to Gulf countries to avoid Syria.

"ARAB LEAGUE IS KILLING US"

Arab governments called off a foreign ministers' meeting due to discuss a response on Saturday to Assad's iron fist policy towards unrest, Egypt's state news agency MENA reported.

A source at Arab League headquarters in Cairo did not give a reason for the cancellation. A lower-level meeting of its ministerial committee on Syria will go ahead in Qatar on Saturday, the source said. The committee includes the foreign ministers of Egypt, Sudan, Oman, Qatar and Algeria.

Friday's protests were held under the slogan of "The Arab League is Killing us," reflecting demonstrators' frustration at what they see as the organization's ponderous response.

At the U.N. Security Council in October, Russia and China vetoed a West European draft resolution that threatened sanctions. Russia has circulated its own draft twice but Western nations said they had made unacceptable attempts to assign blame equally to government and opposition for the violence.

The draft floated unexpectedly by Russia on Thursday expands and toughens Moscow's previous text, adding a new reference to "disproportionate use of force by Syrian authorities."

Obtained by Reuters, the draft also "urges the Syrian government to put an end to suppression of those exercising their rights to freedom of expression, peaceful assembly and association."

Reports by Human Rights Watch and a U.N.-backed independent investigation have assessed that Syrian government forces were given "shoot to kill" orders when confronting demonstrators.

STRONGER TEXT

Russia's U.N. Ambassador, Vitaly Churkin, told reporters that the latest draft resolution "considerably strengthens all aspects of the previous text" and that "clearly the Syrian authorities are singled out in a number of instances."

He said Russia did not believe both sides in Syria were equally responsible for violence, but acknowledged the text called on all parties to halt violence and contained no threat of sanctions, which he said Moscow continued to oppose.

Western officials welcomed the Russian move, but French Ambassador Gerard Araud said it needed "a lot of amendments."

U.S. Secretary of State Hillary Clinton said she could not support some parts of the draft but "hopefully we can work with the Russians, who for the first time at least are recognizing that this is a matter that needs to go to the Security Council."

In London, British Foreign Office Minister Alistair Burt said Russia might hold the key to tightening sanctions on Syria, but Britain would also look at ways of imposing new measures on Damascus through the European Union.

"We will continue to look for new ways in energy, in transport, as well as financial restrictions, to put pressure on the Syrian regime," Burt told Reuters in a telephone interview.

(Additional reporting by Khaled Yacoub Oweis in Amman, Ece Toksabay in Ankara and Tom Pfeiffer in Cairo; Editing by Mark Heinrich)

Source: http://us.rd.yahoo.com/dailynews/rss/un/*http%3A//news.yahoo.com/s/nm/20111216/wl_nm/us_syria

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